Natural CD8+CD122+ T Cells Are More Potent in Suppression of Allograft Rejection Than CD4+CD25+ Regulatory T Cells
نویسندگان
چکیده
منابع مشابه
Regulatory CD4+CD25+T cells in prevention of allograft rejection.
Long-term survival of transplanted organs currently requires chronic immunosuppressive treatment of recipients. While the efficacy of these therapies is satisfactory, their toxicity to host tissues and non-specific inhibition of the immune response are disadvantageous. The ideal in transplantation is a situation of donor-specific unresponsiveness, but agents capable of effecting specific tolera...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2013
ISSN: 1600-6135
DOI: 10.1111/ajt.12515